Fatty acid esters
Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 50mg
Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents
Medchemexpress LLC Lauric anhydride 10g
Lauric anhydride is a white waxy solid used as an intermediate in the production of various chemicals It is primarily used in the synthesis of surfactants emulsifiers and lubricants and as a raw material for other important industrial chemicals such as plasticizers and flavoring agents It can be obtained from natural sources such as palm kernel oil and coconut oil and its unique chemical structure allows it to be used to create compounds with specific surface and interfacial properties
Medchemexpress LLC Monomethyl auristatin E intermediate-1 | 120205-48-3 | 99.5% | 295.85 | 5 G
Monomethyl auristatin E intermediate-1 is an intermediate reagent used in the synthesis of Monomethyl auristatin E (MMAE). MMAE is a microtubule/tubulin inhibitor with anticancer activity, and it is widely utilized as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). This product is for research use only and not for sale to patients.
- Appearance: Solid
- Color: White to off-white
- Formula: C14H30ClNO3
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, stored under nitrogen, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (stored under nitrogen, away from moisture).
Sigma Aldrich Fine Chemicals Biosciences Methyl octanoate 99 fG
Methyl octanoate has been identified in the volatile flavor fractions of blue cheese and soursop.
Medchemexpress LLC Oleic acid (sodium) | 143-19-1 | 304.44 | 1 G
Oleic acid (sodium) | 143-19-1 | 304.44 | 1 G
AdipoGen 4-Methylumbelliferyl butyrate
Chemical. CAS 17695-46-4. Formula C14H14O4. MW 246.26. Synthetic. Fluorogenic substrate for butyrate esterase.
TARGETMOL CHEMICALS INC PHORBOL 12-MYRISTATE 13- 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Phorbol 12-myristate 13-acetate (PMA) (PMA) is a dual SphK and PKC activator. purity: 99%
Medchemexpress LLC MK-0812 Succinate | 851916-42-2 | 99.9% | C28H40F3N3O7 | 50 MG
MK-0812 Succinate is a potent and selective CCR2 antagonist with high affinity at CCR2. It appears as a white to off-white solid and is soluble in DMSO.
- Potent and selective CCR2 antagonist
- High affinity at CCR2
- Appearance: white to off-white solid
- In vitro solubility: ≥ 32 mg/mL (54.46 mM) in DMSO
- Shipping at room temperature
- Storage at 4°C, sealed, away from moisture
- Storage in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Polyoxyl 40 stearate | 171286-89-8 | 98.0% | 2046.58 | C98H196O42 | 5 G
Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant and pharmaceutical excipient used to improve solubility, stability, and processability of drug formulations. It functions as an emulsifying agent and solubilizer for hydrophobic active ingredients across topical, oral, and parenteral preparations.
- Nonionic surfactant and emulsifier.
- Improves solubility of hydrophobic compounds.
- Enhances formulation stability and processability.
- Suitable for topical, oral, and parenteral applications.
- High apparent purity (98.0%).
- Available in small research quantities (1 g-50 g).
Chemscene ChemScene | Sodium nonanoate | 100G | CS-0185612 | 0.97 | 14047-60-0| MFCD00069612 | 180.22
ChemScene | Sodium nonanoate | 100G | CS-0185612 | 0.97 | 14047-60-0| MFCD00069612 | 180.22
Medchemexpress LLC Diethyl succinate-13C4 | 1628796-56-4 | 178.16 | C4(13C4)H14O4 | 1mg
Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1] Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes incorporates into cells in tissue culture and is metabolized by the TCA cycle Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2]
Medchemexpress LLC Butanedioic-2,2,3,3-d4 acid, 1,4-dimethyl ester | 30994-23-1 | MFCD00190428 | 99.5% | 150.17 g/mol | C6H6D4O4 | 50mg
Dimethyl succinate-d4 is the deuterium labeled Dimethyl succinate[1]